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The use of biophysical methods in the hit-to-lead process
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2bind GmbH - Thomas Schubert - MST - NanoTemper Technologies
WebMiriam Jauset Rubio 1 , Markéta Svobodová 1 , Teresa Mairal 1 , Thomas Schubert 2 , Stefan Künne 3 , Günter Mayer 3 , Ciara K O'Sullivan 4 5 Affiliations 1 ... 2 2bind GmbH, Josef … WebDr. Thomas Schubert Lab of Prof. Gernot Längst, University of Regensburg in cooperation with 2bind GmbH, Germany Abstract Histone proteins are associated with DNA and form a nucleoprotein structure termed chromatin. The chromatin structure allows the eukaryotic genome to be stored and transported but also needs to be accessible to WebSep 11, 2024 · CCR5 QTY, CXCR4 QTY, and CXCR7 QTY also bind to HIV coat protein gp41-120. Despite substantial transmembrane domain changes, the detergent-free QTY variants maintain stable structures and retain their ligand-binding activities. We believe the QTY code will be useful for designing water-soluble variants of membrane proteins and other water ... the bridal shoppe lubbock