Rab22a-neof1
WebThe Rab22a-NeoF1 fusion gene has been shown to be expressed in OS and to promote metastasis of OS [144,145,146,147]. In addition, EWSR1-CREB3L1 has been identified as a novel fusion transcript in small-cell OS , and the FN1-FGFR1 fusion gene may be a target in chondroblastoma-like OS . WebNX_Q9UL26 - RAB22A - Ras-related protein Rab-22A - Computed references. Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early …
Rab22a-neof1
Did you know?
WebApr 11, 2024 · Aims: This study aims to formulate the inter-feature correlation as the engineered features. Background: Modern biotechnologies tend to generate a huge number of characteristics of a sample, while an OMIC dataset usually has a few dozens or hundreds of samples due to the high costs of generating the OMIC data. Therefore, many bio-OMIC … WebJun 18, 2024 · Open Access Background: Rab22a-NeoF1 fusion gene containing the 1-38aa of Rab22a (Rab22a1-38) plays a decisive role in driving tumor metastasis by …
WebZong et al. demonstrated for the first time that osteosarcoma cells carrying the RAB22A-NeoF1 fusion gene acts as a metastasizing driver that may secrete exosomes containing … WebFeb 11, 2024 · Rab22a-NeoF1 fusion protein promotes osteosarcoma lung metastasis through its secretion into exosomes. Li Zhong; Dan Liao; Tiebang Kang; Article Open Access 11 Feb 2024.
WebThe prognostic value of a Methylome-based Malignancy Density Scoring System to predict recurrence risk in early-stage Lung Adenocarcinoma Lu Yang, Jing Zhang, Guangjian Yang, Haiyan Xu, Jing Lin, Lin Shao, Junling Li, Changyuan Guo, Yanru Du, Lei Guo, Xin Li, Han Han-Zhang, Chenyang Wang, Shannon Chuai, Junyi Ye, Qiaolin Kang, Hao Liu, Jianming Ying, … WebDec 19, 2024 · PINK1 is able to phosphorylate Rab22a-NeoF1 at serine120, which promotes ubiquitination and degradation of Rab22a-NeoF1. Consistently, by upregulating PINK1, …
Web本发明公开了一种用于治疗骨肉瘤的靶向多肽及其应用；所述多肽的氨基酸序列如seq id no.1或seq id no.2所示；体外实验结果显示 ...
WebFeb 10, 2024 · Signal Transduction and Targeted Therapy volume 6, Article number: 59 (2024) Cite this article. It remains unknown for decades how some of the therapeutic … negative effects of listening to musicWebAug 24, 2024 · Europe PMC is an archive of life sciences journal literature. negative effects of low vitamin dWebFeb 12, 2024 · The exosomal Rab22a-NeoF1 fusion protein facilitates the pulmonary pre-metastatic niche formation by recruiting bone marrow-derived macrophages. The exosomal PYK2 activates RhoA in its negative recipient osteosarcoma cells and induces signal transducer and activator of transcription 3 activation in its recipient macrophages to … negative effects of low testosteroneWebAug 24, 2024 · This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our … negative effects of long term breastfeedingWebZong et al. demonstrated for the first time that osteosarcoma cells carrying the RAB22A-NeoF1 fusion gene acts as a metastasizing driver that may secrete exosomes containing RAB22A-NeoF1 into the osteosarcoma microenvironment, thereby affecting the characteristics of RAB22A-NeoF1-negative osteosarcoma cells. itihastwelveWebAbstract. Background: Rab22a-NeoF1 fusion gene containing the 1-38aa of Rab22a (Rab22a 1-38) plays a decisive role in driving tumor metastasis by activating RhoA via binding to SmgGDS607.However, its intercellular regulation remains unknown. Methods: The Lys7 (K7) acetylation of Rab22a-NeoF1 was initially identified by mass spectrum. Co-transfection, … negative effects of low self esteemWebFeb 11, 2024 · Rab22a-NeoF1 fusion protein is secreted into media and enhances lung metastasis. Since osteosarcoma has a high heterogeneity, the RAB22A-NeoF1 fusion … iti hathbandh